<?xml version="1.0" encoding="UTF-8"?>
<html xmlns="http://www.w3.org/1999/xhtml" xmlns:wx="http://ilps.science.uva.nl/WikiXML/wx" xml:lang="it" lang="it">
<head>
<title>Neurochinina A</title>
<meta name="wx_namespace" content="0"/>
<meta name="wx_pagename" content="Neurochinina_A"/>
<meta name="wx_page_id" content="1460699"/>
</head>
<body>
<div id="wx_article">
<wx:section level="1" title="Neurochinina A" id="wxsec1"><h1 class="pagetitle" id="wx1">Neurochinina A</h1>

<wx:template id="wx_t11" pagename="Template:Composto_chimico" page_id="540752"/>
<table align="right" width="300" border="1" cellspacing="0" cellpadding="3" style="margin-left:0.5em; margin-bottom:0.5em; border-collapse:collapse; font-size:95%; border:1px #aaaaaa solid;" bgcolor="#efefef" id="wx2">
<tr id="wx3">
<td colspan="2" align="center" bgcolor="#AADDFF" id="wx4"><b id="wx5">Neurochinina A</b> </td>
</tr>

<tr id="wx6">
<td align="center" colspan="2" id="wx7"><a href="/wit/Immagine:Neurokinin_A.png" title="Neurochinina A" wx:linktype="image" wx:pagename="Immagine:Neurokinin_A.png" id="wx8"><img src="/wit/Immagine:Neurokinin_A.png" alt="Neurochinina A" width="300" id="wx9"/></a></td>
</tr>

<tr id="wx10">
<td bgcolor="#DDEEFF" id="wx11"><a href="/wit/Formula_bruta" title="Formula bruta" wx:linktype="known" wx:pagename="Formula_bruta" wx:page_id="1925" id="wx12">Formula bruta</a>
<p id="wx13">o molecolare</p>
</td>
<td id="wx14">
<p id="wx15">C<sub id="wx16">50</sub>H<sub id="wx17">80</sub>N<sub id="wx18">14</sub>O<sub id="wx19">14</sub>S</p>
</td>
</tr>

<tr id="wx20">
<td bgcolor="#DDEEFF" id="wx21"><a href="/wit/Massa_molecolare" title="Massa molecolare" wx:linktype="known" wx:pagename="Massa_molecolare" wx:page_id="37763" id="wx22">Massa molecolare</a>
<p id="wx23">(<a href="/wit/Unit%C3%A0_di_massa_atomica" title="Unità di massa atomica" wx:linktype="known" wx:pagename="Unità_di_massa_atomica" wx:page_id="63420" id="wx24">u</a>)</p>
</td>
<td id="wx25">
<p id="wx26">1133,32</p>
</td>
</tr>

<tr id="wx27">
<td bgcolor="#DDEEFF" id="wx28"><a href="/wit/Numero_CAS" title="Numero CAS" wx:linktype="known" wx:pagename="Numero_CAS" wx:page_id="24648" id="wx29">Numero CAS</a> </td>
<td id="wx30">
<p id="wx31">86933-74-6</p>
</td>
</tr>

<tr id="wx32">
<td bgcolor="#AADDFF" colspan="2" align="center" id="wx33"><b id="wx34">Indicazioni di sicurezza</b> </td>
</tr>

<tr id="wx35">
<th colspan="2" id="wx36">
<p id="wx37">     <br id="wx38"/>
</p>

<hr id="wx39"/>
<div style="text-align:center; font-size:90%" id="wx40">
<p id="wx41">Le sostanze chimiche vanno manipolate con cautela<br id="wx42"/>
<b id="wx43"><a href="/wit/Wikipedia:Disclaimer_sul_rischio" title="Wikipedia:Disclaimer sul rischio" wx:linktype="known" wx:pagename="Wikipedia:Disclaimer_sul_rischio" id="wx44">Avvertenze</a></b></p>
</div>
</th>
</tr>

<tr id="wx45">
<th bgcolor="#AADDFF" colspan="2" id="wx46"><small id="wx47"><a href="/wit/Progetto:Chimica/Composti" class="new" title="Progetto:Chimica/Composti" wx:linktype="unknown" wx:pagename="Progetto:Chimica/Composti" id="wx48">Progetto composti</a></small> </th>
</tr>
</table>

<wx:templateend start="wx_t11"/>
<wx:template id="wx_t12" pagename="Template:Proteina" page_id="530919"/>
<table style="clear:right; margin:.5em; text-align:center; float:right" width="230px" class="toccolours itwiki_template_toc radius" id="wx49">
<tr id="wx50">
<th width="100%" style="-moz-border-radius-topleft:.9em; background:#C2C3FF; border:1px solid #88A" id="wx51">
<p id="wx52">Precursore 1 della tachichinina</p>
</th>
<td style="-moz-border-radius-topright:.9em; background:#C2C3FF; border:1px solid #88A" id="wx53">
<p id="wx54"><span style="position:relative; overflow:hidden; width:20px; height:20px; z-index:2" id="wx55"><a href="/wit/Immagine:Nuvola_apps_katomic.svg" title="" wx:linktype="image" wx:pagename="Immagine:Nuvola_apps_katomic.svg" id="wx56"><img src="/wit/Immagine:Nuvola_apps_katomic.svg" alt="" width="20" id="wx57"/></a><span style="position:absolute; top:0; left:0; padding-top:3px; z-index:3; text-decoration:none" id="wx58"><a href="/wit/Progetto:Bio" class="new" title="Progetto:Bio" wx:linktype="unknown" wx:pagename="Progetto:Bio" id="wx59"><span style="float:left; width:20px; height:20px; font-size:20px; line-height:20px; word-spacing:20px; cursor:pointer" id="wx60">   </span></a></span></span></p>
</td>
</tr>

<tr id="wx61">
<td colspan="3" style="background:#FFFFFF; font-size:100%" id="wx62">
<table style="background:#FFF; text-align:left; width:100%;" id="wx63">
<tr id="wx64">
<td class="hiddenStructureSubstance_P.png" align="center" colspan="2" id="wx65"><a href="/wit/Immagine:Substance_P.png" title="Neurochinina A struttura chimica" wx:linktype="image" wx:pagename="Immagine:Substance_P.png" id="wx66"><img src="/wit/Immagine:Substance_P.png" alt="Neurochinina A struttura chimica" width="280" id="wx67"/></a> </td>
</tr>

<tr style="text-align: center; line-height: 1;" class="hiddenStructurePrecursore della Tachichinina A" id="wx68">
<td colspan="2" id="wx69"><small id="wx70"><i id="wx71">Precursore della Tachichinina A</i></small> </td>
</tr>

<tr id="wx72">
<td colspan="2" style="background:#E2F3EF; border-top:2px solid #C2C3FF" id="wx73"><b id="wx74"><a href="/wit/Gene" title="Gene" wx:linktype="known" wx:pagename="Gene" wx:page_id="1723644" id="wx75">Gene</a></b> </td>
</tr>

<tr class="hiddenStructureTAC1" id="wx76">
<td id="wx77"><i id="wx78"><a href="/wit/HUGO" title="HUGO" wx:linktype="known" wx:pagename="HUGO" wx:page_id="679797" id="wx79">HUGO</a></i> </td>
<td id="wx80"><a href="http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?gd_app_sym=TAC1" class="external text" wx:linktype="external" rel="nofollow" id="wx81">TAC1</a>
<p id="wx82">TAC2, NKNA</p>
</td>
</tr>

<tr class="hiddenStructure6863" id="wx83">
<td id="wx84"><i id="wx85"><a href="/wit/Entrez" title="Entrez" wx:linktype="known" wx:pagename="Entrez" wx:page_id="681159" id="wx86">Entrez</a></i> </td>
<td id="wx87"><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&amp;cmd=retrieve&amp;dopt=default&amp;list_uids=6863&amp;rn=1" class="external text" wx:linktype="external" rel="nofollow" id="wx88">6863</a> </td>
</tr>

<tr class="hiddenStructure7" id="wx89">
<td id="wx90"><a href="/wit/Locus" title="Locus" wx:linktype="known" wx:pagename="Locus" wx:page_id="679899" id="wx91">Locus</a> </td>
<td id="wx92"><a href="/wit/Cromosoma_7_%28umano%29" title="Cromosoma 7 (umano)" wx:linktype="known" wx:pagename="Cromosoma_7_(umano)" wx:page_id="836678" id="wx93">Chr. 7</a> <i id="wx94"><a href="http://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=7q21" class="external text" wx:linktype="external" rel="nofollow" id="wx95">q21-q22</a></i> </td>
</tr>

<tr id="wx96">
<td colspan="2" style="background:#E2F3EF; border-top:2px solid #C2C3FF" id="wx97"><b id="wx98"><a href="/wit/Proteina" title="Proteina" wx:linktype="known" wx:pagename="Proteina" wx:page_id="3451" id="wx99">Proteina</a></b> </td>
</tr>

<tr class="hiddenStructure162320" id="wx100">
<td id="wx101"><i id="wx102"><a href="/wit/OMIM" title="OMIM" wx:linktype="known" wx:pagename="OMIM" wx:page_id="679997" id="wx103">OMIM</a></i> </td>
<td id="wx104"><a href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=162320&amp;rn=1" class="external text" wx:linktype="external" rel="nofollow" id="wx105">162320</a> </td>
</tr>

<tr class="hiddenStructureP20366" id="wx106">
<td id="wx107"><i id="wx108"><a href="/wit/Swiss-Prot" title="Swiss-Prot" wx:linktype="known" wx:pagename="Swiss-Prot" wx:page_id="686076" id="wx109">UniProt</a></i> </td>
<td id="wx110"><a href="http://www.expasy.org/cgi-bin/niceprot.pl?P20366" class="external text" wx:linktype="external" rel="nofollow" id="wx111">P20366</a> </td>
</tr>

<tr class="hiddenStructure" id="wx112">
<td id="wx113"><i id="wx114"><a href="/wit/Protein_Data_Bank" title="Protein Data Bank" wx:linktype="known" wx:pagename="Protein_Data_Bank" wx:page_id="653554" id="wx115">PDB</a></i> </td>
<td id="wx116"><a href="http://www.pdb.org/pdb/cgi/explore.cgi?pdbId=" class="external autonumber" wx:linktype="external" rel="nofollow" id="wx117"/> </td>
</tr>

<tr class="hiddenStructure" id="wx118">
<td colspan="2" style="background:#E2F3EF; border-top:2px solid #C2C3FF" id="wx119"><b id="wx120"><a href="/wit/Enzima" title="Enzima" wx:linktype="known" wx:pagename="Enzima" wx:page_id="21081" id="wx121">Enzima</a></b> </td>
</tr>

<tr class="hiddenStructure" id="wx122">
<td id="wx123"><i id="wx124"><a href="/wit/Classificazione_EC" title="Classificazione EC" wx:linktype="known" wx:pagename="Classificazione_EC" wx:page_id="419349" id="wx125">EC number</a></i> </td>
<td id="wx126"><a href="http://www.genome.ad.jp/dbget-bin/www_bget?ec:" class="external autonumber" wx:linktype="external" rel="nofollow" id="wx127"/> </td>
</tr>

<tr id="wx128">
<td colspan="2" style="background:#FFC253; -moz-border-radius-bottomright:.9em; -moz-border-radius-bottomleft:.9em; border:1px solid #88A" id="wx129">
<div style="text-align:center;" id="wx130"><small id="wx131"><b id="wx132"><a href="/wit/Progetto:Bio" class="new" title="Progetto:Bio" wx:linktype="unknown" wx:pagename="Progetto:Bio" id="wx133"><span style="color:black" id="wx134">Vai al <i id="wx135">Progetto Bio</i></span></a></b><br id="wx136"/>
<b id="wx137"><a href="/wit/Discussioni_progetto:Bio" class="new" title="Discussioni progetto:Bio" wx:linktype="unknown" wx:pagename="Discussioni_progetto:Bio" id="wx138"><span style="color:black" id="wx139">Discuti alla <i id="wx140">Doppia Elica</i></span></a></b></small></div>
</td>
</tr>
</table>
</td>
</tr>
</table>

<wx:templateend start="wx_t12"/>
<p id="wx141">La <b id="wx142">Neurochinina A</b> (un tempo nota come <b id="wx143">Sostanza K</b>) è un <a href="/wit/Neuropeptide" class="new" title="Neuropeptide" wx:linktype="unknown" wx:pagename="Neuropeptide" id="wx144">neuropeptide</a>, un <a href="/wit/Peptide" title="Peptide" wx:linktype="known" wx:pagename="Peptide" wx:page_id="514638" id="wx145">polipeptide</a> a catena corta, appartenente alla famiglia delle <a href="/wit/Tachichinina" title="Tachichinina" wx:linktype="known" wx:pagename="Tachichinina" wx:page_id="1450640" id="wx146">tachichinine</a>, che agisce da <a href="/wit/Neurotrasmettitore" title="Neurotrasmettitore" wx:linktype="known" wx:pagename="Neurotrasmettitore" wx:page_id="51612" id="wx147">neurotrasmettitore</a> nei <a href="/wit/Mammiferi" title="Mammiferi" wx:linktype="known" wx:pagename="Mammiferi" wx:page_id="106347" id="wx148">mammiferi</a><sup id="_ref-0" class="reference"><a href="#_note-0" title="" wx:fragment="_note-0" wx:linktype="note" id="wx149"/></sup>.</p>

<div id="wx_toc"/>

<a id="Struttura" name="Struttura"/>
<wx:section level="2" title="Struttura" id="wxsec2"><h2 id="wx150">Struttura</h2>

<p id="wx151">Il polipeptide è composto da 10 <a href="/wit/Aminoacido" title="Aminoacido" wx:linktype="known" wx:pagename="Aminoacido" wx:page_id="79602" id="wx152">aminoacidi</a> con sequenza: <i id="wx153"><a href="/wit/Dominio_C-terminale" title="Dominio C-terminale" wx:linktype="known" wx:pagename="Dominio_C-terminale" wx:page_id="734135" id="wx154">C-terminale</a>-<a href="/wit/Istidina" title="Istidina" wx:linktype="known" wx:pagename="Istidina" wx:page_id="50973" id="wx155">His</a>-<a href="/wit/Lisina" title="Lisina" wx:linktype="known" wx:pagename="Lisina" wx:page_id="51006" id="wx156">Lys</a>-<a href="/wit/Treonina" title="Treonina" wx:linktype="known" wx:pagename="Treonina" wx:page_id="51153" id="wx157">Thr</a>-<a href="/wit/Asparagina" title="Asparagina" wx:linktype="known" wx:pagename="Asparagina" wx:page_id="51046" id="wx158">Asn</a>-<a href="/wit/Serina" title="Serina" wx:linktype="known" wx:pagename="Serina" wx:page_id="39141" id="wx159">Ser</a>-<a href="/wit/Fenilalanina" title="Fenilalanina" wx:linktype="known" wx:pagename="Fenilalanina" wx:page_id="252647" id="wx160">Phe</a>-<a href="/wit/Valina" title="Valina" wx:linktype="known" wx:pagename="Valina" wx:page_id="51157" id="wx161">Val</a>-<a href="/wit/Glicina" title="Glicina" wx:linktype="known" wx:pagename="Glicina" wx:page_id="50807" id="wx162">Gly</a>-<a href="/wit/Leucina" title="Leucina" wx:linktype="known" wx:pagename="Leucina" wx:page_id="51021" id="wx163">Leu</a>-<a href="/wit/Metionina" title="Metionina" wx:linktype="known" wx:pagename="Metionina" wx:page_id="51037" id="wx164">Met</a>-<a href="/wit/Dominio_N-terminale" title="Dominio N-terminale" wx:linktype="known" wx:pagename="Dominio_N-terminale" wx:page_id="734217" id="wx165">N-terminale</a></i><sup id="_ref-1" class="reference"><a href="#_note-1" title="" wx:fragment="_note-1" wx:linktype="note" id="wx166"/></sup>.</p>

<p id="wx167">La <a href="/wit/Dominio_N-terminale" title="Dominio N-terminale" wx:linktype="known" wx:pagename="Dominio_N-terminale" wx:page_id="734217" id="wx168">regione N-terminale</a> non è essenziale per l'attività. Sono essenziali per l'attività invece i frammenti contenenti l'estremità <a href="/wit/Dominio_N-terminale" title="Dominio N-terminale" wx:linktype="known" wx:pagename="Dominio_N-terminale" wx:page_id="734217" id="wx169">N-terminale</a>: gli ultimi cinque (6-10) <a href="/wit/Peptide" title="Peptide" wx:linktype="known" wx:pagename="Peptide" wx:page_id="514638" id="wx170">peptidi</a> sono infatti attivi quanto, e talora anche di più, il peptide completo dei dieci aminoacidi<sup id="_ref-2" class="reference"><a href="#_note-2" title="" wx:fragment="_note-2" wx:linktype="note" id="wx171"/></sup>.</p>

<a id="Sintesi" name="Sintesi"/>
</wx:section><wx:section level="2" title="Sintesi" id="wxsec3"><h2 id="wx172">Sintesi</h2>

<p id="wx173">La sintesi delle tachichinine si verifica soprattutto dai <a href="/wit/Neurone" title="Neurone" wx:linktype="known" wx:pagename="Neurone" wx:page_id="19749" id="wx174">neuroni</a> e i peptidi sono liberati dagli <a href="/wit/Assone" title="Assone" wx:linktype="known" wx:pagename="Assone" wx:page_id="109320" id="wx175">assoni</a>. Di recente è stata dimostrata produzione di neuropeptidi anche da cellule extraneuronali, come <a href="/wit/Granulocita_eosinofilo" title="Granulocita eosinofilo" wx:linktype="known" wx:pagename="Granulocita_eosinofilo" wx:page_id="338655" id="wx176">granulociti eosinofili</a>, <a href="/wit/Macrofago" title="Macrofago" wx:linktype="known" wx:pagename="Macrofago" wx:page_id="97151" id="wx177">macrofagi</a>, <a href="/wit/Linfocita" title="Linfocita" wx:linktype="known" wx:pagename="Linfocita" wx:page_id="89940" id="wx178">linfociti</a>. La produzione della Neurochinina A, come pure della Sostanza P, del Neuropeptide K e del Neuropeptide Y, è regolata dal gene preprotachichinina-I (PPT-I o PPT-A) che, per motivi storici, è chiamato negli uomini TAC1 e TAC3, ed è equivalente al gene Tac1 del <a href="/wit/Topo" title="Topo" wx:linktype="known" wx:pagename="Topo" wx:page_id="500655" id="wx179">topo</a><sup id="_ref-3" class="reference"><a href="#_note-3" title="" wx:fragment="_note-3" wx:linktype="note" id="wx180"/></sup>. Le preprotachichinine sono poi tagliate in polipeptidi più piccoli.</p>

<a id="Recettore" name="Recettore"/>
</wx:section><wx:section level="2" title="Recettore" id="wxsec4"><h2 id="wx181">Recettore</h2>

<p id="wx182">Il <a href="/wit/Recettore_%28biochimica%29" title="Recettore (biochimica)" wx:linktype="known" wx:pagename="Recettore_(biochimica)" wx:page_id="1447459" id="wx183">recettore</a> endogeno della Sostanza P è il recettore 1 della neurochinina (NK1R), appartenente alla famiglia dei <a href="/wit/Recettori_accoppiati_a_proteine_G" title="Recettori accoppiati a proteine G" wx:linktype="known" wx:pagename="Recettori_accoppiati_a_proteine_G" wx:page_id="1335973" id="wx184">recettori accoppiati a proteine G</a><sup id="_ref-4" class="reference"><a href="#_note-4" title="" wx:fragment="_note-4" wx:linktype="note" id="wx185"/></sup>, <sup id="_ref-5" class="reference"><a href="#_note-5" title="" wx:fragment="_note-5" wx:linktype="note" id="wx186"/></sup>.</p>

<a id="Meccanismo_d.27azione" name="Meccanismo_d.27azione"/>
</wx:section><wx:section level="2" title="Meccanismo d'azione" id="wxsec5"><h2 id="wx187">Meccanismo d'azione</h2>

<p id="wx188">La Neurochinina A svolge diverse funzioni nell'organismo animale. Come tutte le <a href="/wit/Tachichinina" title="Tachichinina" wx:linktype="known" wx:pagename="Tachichinina" wx:page_id="1450640" id="wx189">tachichinine</a>, la Neurochinina A è in grado di eccitare <a href="/wit/Neurone" title="Neurone" wx:linktype="known" wx:pagename="Neurone" wx:page_id="19749" id="wx190">neuromi</a><sup id="_ref-6" class="reference"><a href="#_note-6" title="" wx:fragment="_note-6" wx:linktype="note" id="wx191"/></sup>, <a href="/wit/Vasodilatatore" title="Vasodilatatore" wx:linktype="known" wx:pagename="Vasodilatatore" wx:page_id="1567007" id="wx192">dilatare i vasi sanguigni</a><sup id="_ref-7" class="reference"><a href="#_note-7" title="" wx:fragment="_note-7" wx:linktype="note" id="wx193"/></sup> e far contrarre la muscolatura liscia per esempio quella della parete <a href="/wit/Vescica" title="Vescica" wx:linktype="known" wx:pagename="Vescica" wx:page_id="574892" id="wx194">vescicale</a>, <a href="/wit/Utero" title="Utero" wx:linktype="known" wx:pagename="Utero" wx:page_id="690434" id="wx195">uterina</a> o delle <a href="/wit/Apparato_respiratorio" title="Apparato respiratorio" wx:linktype="known" wx:pagename="Apparato_respiratorio" wx:page_id="702531" id="wx196">vie aeree</a><sup id="_ref-8" class="reference"><a href="#_note-8" title="" wx:fragment="_note-8" wx:linktype="note" id="wx197"/></sup>, ed è uno dei principali <a href="/wit/Neurotrasmettitore" title="Neurotrasmettitore" wx:linktype="known" wx:pagename="Neurotrasmettitore" wx:page_id="51612" id="wx198">mediatori</a> della <a href="/wit/Peristalsi" title="Peristalsi" wx:linktype="known" wx:pagename="Peristalsi" wx:page_id="637186" id="wx199">peristalsi</a> <a href="/wit/Intestino" title="Intestino" wx:linktype="known" wx:pagename="Intestino" wx:page_id="691820" id="wx200">intestinale</a><sup id="_ref-9" class="reference"><a href="#_note-9" title="" wx:fragment="_note-9" wx:linktype="note" id="wx201"/></sup>. Non sono invece ben noti gli effetti sul <a href="/wit/Sistema_immunitario" title="Sistema immunitario" wx:linktype="known" wx:pagename="Sistema_immunitario" wx:page_id="691622" id="wx202">sistema immunitario</a>, <sup id="_ref-10" class="reference"><a href="#_note-10" title="" wx:fragment="_note-10" wx:linktype="note" id="wx203"/></sup>.</p>

<p id="wx204">L'estremità attiva <a href="/wit/Dominio_N-terminale" title="Dominio N-terminale" wx:linktype="known" wx:pagename="Dominio_N-terminale" wx:page_id="734217" id="wx205">N-terminale</a> del <i id="wx206">Neuropeptide K</i> (che è stato chiamato anche <i id="wx207">Neurochinina K</i><sup id="_ref-11" class="reference"><a href="#_note-11" title="" wx:fragment="_note-11" wx:linktype="note" id="wx208"/></sup>) e del <i id="wx209">Neuropeptide gamma</i> è più lunga di quella della Neurochinina A, sebbene tutti siano stati prodotti per mezzo dello stesso <a href="/wit/Splicing#Splicing_alternativo" title="Splicing" wx:linktype="known" wx:pagename="Splicing" wx:page_id="359973" wx:fragment="Splicing_alternativo" id="wx210">splicing alternativo</a> del medesimo <a href="/wit/Gene" title="Gene" wx:linktype="known" wx:pagename="Gene" wx:page_id="1723644" id="wx211">gene</a><sup id="_ref-Carter_0" class="reference"><a href="#_note-Carter" title="" wx:fragment="_note-Carter" wx:linktype="note" id="wx212"/></sup>.</p>

<a id="Voci_correlate" name="Voci_correlate"/>
</wx:section><wx:section level="2" title="Voci correlate" id="wxsec6"><h2 id="wx213">Voci correlate</h2>

<ul id="wx214">
<li id="wx215"><a href="/wit/Tachichinina" title="Tachichinina" wx:linktype="known" wx:pagename="Tachichinina" wx:page_id="1450640" id="wx216">Tachichinina</a></li>

<li id="wx217"><a href="/wit/Sostanza_P" title="Sostanza P" wx:linktype="known" wx:pagename="Sostanza_P" wx:page_id="1455875" id="wx218">Sostanza P</a></li>

<li id="wx219"><a href="/wit/Neurochinina_B" title="Neurochinina B" wx:linktype="known" wx:pagename="Neurochinina_B" wx:page_id="1460172" id="wx220">Neurochinina B</a></li>
</ul>

<a id="Note" name="Note"/>
</wx:section><wx:section level="2" title="Note" id="wxsec7"><h2 id="wx221">Note</h2>

<ol class="references" id="wx222">
<li id="_note-0"><a href="#_ref-0" title="" wx:fragment="_ref-0" wx:linktype="noteref" id="wx223"><b id="wx224">^</b></a> <a href="/wit/Vittorio_Erspamer" title="Vittorio Erspamer" wx:linktype="known" wx:pagename="Vittorio_Erspamer" wx:page_id="1447304" id="wx225">Vittorio Erspamer</a>
<p id="wx226">: "Sostanze Bioattive: dalla pelle di un anfibio al cervello di uomo", Prolusione tenuta nell'inaugurazione del 205° Anno Accademico dell'Accademia dei XL, Marzo 1987 <a href="http://www.accademiaxl.it/Biblioteca/Virtuale/Erspamer.htm" class="external autonumber" wx:linktype="external" rel="nofollow" id="wx227"/></p>
</li>

<li id="_note-1"><a href="#_ref-1" title="" wx:fragment="_ref-1" wx:linktype="noteref" id="wx228"><b id="wx229">^</b></a> <wx:template id="wx_t1" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx230">Helke CJ, Krause JE, Mantyh PW, Couture R, Bannon MJ (1990 Apr 1).  <i id="wx231">Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms</i> FASEB J <b id="wx232">4</b> (6): 1606-15. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=1969374" class="external" wx:linktype="external" id="wx233">PMID 1969374</a>.</cite><wx:templateend start="wx_t1"/>
</li>

<li id="_note-2"><a href="#_ref-2" title="" wx:fragment="_ref-2" wx:linktype="noteref" id="wx234"><b id="wx235">^</b></a> <wx:template id="wx_t2" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx236">Clapéron A, Rose C, Gane P, Collec E, Bertrand O, Ouimet (2005 Jun 3).  <i id="wx237">The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein</i> J Biol Chem <b id="wx238">280</b> (22): 21272-83. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=15769748" class="external" wx:linktype="external" id="wx239">PMID 15769748</a>.</cite><wx:templateend start="wx_t2"/>
</li>

<li id="_note-3"><a href="#_ref-3" title="" wx:fragment="_ref-3" wx:linktype="noteref" id="wx240"><b id="wx241">^</b></a> <wx:template id="wx_t3" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx242">Carter MS, Krause JE (1990).  <i id="wx243">Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gamma</i> J Neurosci <b id="wx244">10</b> (7): 2203-14. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=1695945" class="external" wx:linktype="external" id="wx245">PMID 1695945</a>.</cite><wx:templateend start="wx_t3"/></li>

<li id="_note-4"><a href="#_ref-4" title="" wx:fragment="_ref-4" wx:linktype="noteref" id="wx246"><b id="wx247">^</b></a> <wx:template id="wx_t4" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx248">Maggi C, Patacchini R, Rovero P, Giachetti A (1993).  <i id="wx249">Tachykinin receptors and tachykinin receptor antagonists</i> J Auton Pharmacol <b id="wx250">13</b> (1): 23-93. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=8382703" class="external" wx:linktype="external" id="wx251">PMID 8382703</a>.</cite><wx:templateend start="wx_t4"/></li>

<li id="_note-5"><a href="#_ref-5" title="" wx:fragment="_ref-5" wx:linktype="noteref" id="wx252"><b id="wx253">^</b></a> <wx:template id="wx_t5" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx254">Regoli D, Boudon A, Fauchére J (1994).  <i id="wx255">Receptors and antagonists for substance P and related peptides</i> Pharmacol Rev <b id="wx256">46</b> (4): 551-99. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=7534932" class="external" wx:linktype="external" id="wx257">PMID 7534932</a>.</cite><wx:templateend start="wx_t5"/></li>

<li id="_note-6"><a href="#_ref-6" title="" wx:fragment="_ref-6" wx:linktype="noteref" id="wx258"><b id="wx259">^</b></a> <wx:template id="wx_t6" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx260">Chahl LA (2006 Aug).  <i id="wx261">Tachykinins and neuropsychiatric disorders</i> Curr Drug Targets <b id="wx262">7</b> (8): 993-1003. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16918327" class="external" wx:linktype="external" id="wx263">PMID 16918327</a>.</cite><wx:templateend start="wx_t6"/>
</li>

<li id="_note-7"><a href="#_ref-7" title="" wx:fragment="_ref-7" wx:linktype="noteref" id="wx264"><b id="wx265">^</b></a> <wx:template id="wx_t7" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx266">Walsh DA, F McWilliams D (2006 Aug).  <i id="wx267">Tachykinins and the cardiovascular system</i> Curr Drug Targets <b id="wx268">7</b> (8): 1031-42. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16918331" class="external" wx:linktype="external" id="wx269">PMID 16918331</a>.</cite><wx:templateend start="wx_t7"/>
</li>

<li id="_note-8"><a href="#_ref-8" title="" wx:fragment="_ref-8" wx:linktype="noteref" id="wx270"><b id="wx271">^</b></a> <wx:template id="wx_t8" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx272">Groneberg DA, Harrison S, Dinh QT, Geppetti P, Fischer A (2006 Aug).  <i id="wx273">Tachykinins in the respiratory tract</i> Curr Drug Targets <b id="wx274">7</b> (8): 1005-10. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16918328" class="external" wx:linktype="external" id="wx275">PMID 16918328</a>.</cite><wx:templateend start="wx_t8"/>
</li>

<li id="_note-9"><a href="#_ref-9" title="" wx:fragment="_ref-9" wx:linktype="noteref" id="wx276"><b id="wx277">^</b></a> <wx:template id="wx_t9" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx278">Lecci A, Capriati A, Altamura M, Maggi CA (2006 Jun 30).  <i id="wx279">Tachykinins and tachykinin receptors in the gut, with special reference to NK2 receptors in human</i> Auton Neurosci <b id="wx280">126-127</b>: 232-49. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16616700" class="external" wx:linktype="external" id="wx281">PMID 16616700</a>.</cite><wx:templateend start="wx_t9"/></li>

<li id="_note-10"><a href="#_ref-10" title="" wx:fragment="_ref-10" wx:linktype="noteref" id="wx282"><b id="wx283">^</b></a> <wx:template id="wx_t10" pagename="Template:Cita_pubblicazione" page_id="654720"/><cite style="font-style:normal" id="wx284">Zhang Y, Berger A, Milne CD, Paige CJ (2006 Aug).  <i id="wx285">Tachykinins in the immune system</i> Curr Drug Targets <b id="wx286">7</b> (8): 1011-20. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16918329" class="external" wx:linktype="external" id="wx287">PMID 16918329</a>.</cite><wx:templateend start="wx_t10"/>
</li>

<li id="_note-11"><a href="#_ref-11" title="" wx:fragment="_ref-11" wx:linktype="noteref" id="wx288"><b id="wx289">^</b></a>
<p id="wx290">Dornan WA, Vink KL, Malen P, Short K, Struthers W, Barrett C. "Site-specific effects of intracerebral injections of three neurokinins (neurokinin A, neurokinin K, and neurokinin gamma) on the expression of male rat sexual behavior." <i id="wx291">Physiol Behav.</i> 1993 Aug;54(2):249-58. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=7690487" class="external" wx:linktype="external" id="wx292">PMID 7690487</a></p>
</li>

<li id="_note-Carter"><a href="#_ref-Carter_0" title="" wx:fragment="_ref-Carter_0" wx:linktype="noteref" id="wx293"><b id="wx294">^</b></a>
<p id="wx295">Carter MS, Krause JE. "Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gamma." <i id="wx296">J Neurosci.</i> 1990 Jul;10(7):2203-14, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=1695945" class="external" wx:linktype="external" id="wx297">PMID 1695945</a></p>
</li>
</ol>
</wx:section></wx:section></div>
<div id="wx_categorylinks">
<a href="/wit/index.php?title=Speciale:Categories&amp;article=Neurochinina_A" title="Speciale:Categories" wx:linktype="known" wx:pagename="Speciale:Categories" id="wx298">Categorie</a>: <span dir="ltr" id="wx299"><a href="/wit/Categoria:Biomolecole" title="Categoria:Biomolecole" wx:linktype="known" wx:pagename="Categoria:Biomolecole" wx:page_id="499652" id="wx300">Biomolecole</a></span> | <span dir="ltr" id="wx301"><a href="/wit/Categoria:Neurotrasmettitori" title="Categoria:Neurotrasmettitori" wx:linktype="known" wx:pagename="Categoria:Neurotrasmettitori" wx:page_id="787673" id="wx302">Neurotrasmettitori</a></span></div>
<div id="wx_languagelinks">
Altre lingue: <a href="http://en.wikipedia.org/wiki/Neurokinin_A" class="external" wx:linktype="interwiki" wx:pagename="en:Neurokinin_A" id="wx303">English</a></div>
</body>
<wx:templatearguments for="wx_t1"><wx:argument name="autore">
<p id="wx304">Helke CJ, Krause JE, Mantyh PW, Couture R, Bannon MJ</p>
</wx:argument><wx:argument name="titolo">
<p id="wx305">Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms</p>
</wx:argument><wx:argument name="rivista">
<p id="wx306">FASEB J</p>
</wx:argument><wx:argument name="volume">
<p id="wx307">4</p>
</wx:argument><wx:argument name="numero">
<p id="wx308">6</p>
</wx:argument><wx:argument name="pagine">
<p id="wx309">1606-15</p>
</wx:argument><wx:argument name="anno">
<p id="wx310">1990 Apr 1</p>
</wx:argument><wx:argument name="id">
<p id="wx311">PMID 1969374</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t2"><wx:argument name="autore">
<p id="wx312">Clapéron A, Rose C, Gane P, Collec E, Bertrand O, Ouimet</p>
</wx:argument><wx:argument name="titolo">
<p id="wx313">The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein</p>
</wx:argument><wx:argument name="rivista">
<p id="wx314">J Biol Chem</p>
</wx:argument><wx:argument name="volume">
<p id="wx315">280</p>
</wx:argument><wx:argument name="numero">
<p id="wx316">22</p>
</wx:argument><wx:argument name="pagine">
<p id="wx317">21272-83</p>
</wx:argument><wx:argument name="anno">
<p id="wx318">2005 Jun 3</p>
</wx:argument><wx:argument name="id">
<p id="wx319">PMID 15769748</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t3"><wx:argument name="autore">
<p id="wx320">Carter MS, Krause JE</p>
</wx:argument><wx:argument name="titolo">
<p id="wx321">Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gamma</p>
</wx:argument><wx:argument name="rivista">
<p id="wx322">J Neurosci</p>
</wx:argument><wx:argument name="volume">
<p id="wx323">10</p>
</wx:argument><wx:argument name="numero">
<p id="wx324">7</p>
</wx:argument><wx:argument name="pagine">
<p id="wx325">2203-14</p>
</wx:argument><wx:argument name="anno">
<p id="wx326">1990</p>
</wx:argument><wx:argument name="id">
<p id="wx327">PMID 1695945</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t4"><wx:argument name="autore">
<p id="wx328">Maggi C, Patacchini R, Rovero P, Giachetti A</p>
</wx:argument><wx:argument name="titolo">
<p id="wx329">Tachykinin receptors and tachykinin receptor antagonists</p>
</wx:argument><wx:argument name="rivista">
<p id="wx330">J Auton Pharmacol</p>
</wx:argument><wx:argument name="volume">
<p id="wx331">13</p>
</wx:argument><wx:argument name="numero">
<p id="wx332">1</p>
</wx:argument><wx:argument name="pagine">
<p id="wx333">23-93</p>
</wx:argument><wx:argument name="anno">
<p id="wx334">1993</p>
</wx:argument><wx:argument name="id">
<p id="wx335">PMID 8382703</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t5"><wx:argument name="autore">
<p id="wx336">Regoli D, Boudon A, Fauchére J</p>
</wx:argument><wx:argument name="titolo">
<p id="wx337">Receptors and antagonists for substance P and related peptides</p>
</wx:argument><wx:argument name="rivista">
<p id="wx338">Pharmacol Rev</p>
</wx:argument><wx:argument name="volume">
<p id="wx339">46</p>
</wx:argument><wx:argument name="numero">
<p id="wx340">4</p>
</wx:argument><wx:argument name="pagine">
<p id="wx341">551-99</p>
</wx:argument><wx:argument name="anno">
<p id="wx342">1994</p>
</wx:argument><wx:argument name="id">
<p id="wx343">PMID 7534932</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t6"><wx:argument name="autore">
<p id="wx344">Chahl LA</p>
</wx:argument><wx:argument name="titolo">
<p id="wx345">Tachykinins and neuropsychiatric disorders</p>
</wx:argument><wx:argument name="rivista">
<p id="wx346">Curr Drug Targets</p>
</wx:argument><wx:argument name="volume">
<p id="wx347">7</p>
</wx:argument><wx:argument name="numero">
<p id="wx348">8</p>
</wx:argument><wx:argument name="pagine">
<p id="wx349">993-1003</p>
</wx:argument><wx:argument name="anno">
<p id="wx350">2006 Aug</p>
</wx:argument><wx:argument name="id">
<p id="wx351">PMID 16918327</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t7"><wx:argument name="autore">
<p id="wx352">Walsh DA, F McWilliams D</p>
</wx:argument><wx:argument name="titolo">
<p id="wx353">Tachykinins and the cardiovascular system</p>
</wx:argument><wx:argument name="rivista">
<p id="wx354">Curr Drug Targets</p>
</wx:argument><wx:argument name="volume">
<p id="wx355">7</p>
</wx:argument><wx:argument name="numero">
<p id="wx356">8</p>
</wx:argument><wx:argument name="pagine">
<p id="wx357">1031-42</p>
</wx:argument><wx:argument name="anno">
<p id="wx358">2006 Aug</p>
</wx:argument><wx:argument name="id">
<p id="wx359">PMID 16918331</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t8"><wx:argument name="autore">
<p id="wx360">Groneberg DA, Harrison S, Dinh QT, Geppetti P, Fischer A</p>
</wx:argument><wx:argument name="titolo">
<p id="wx361">Tachykinins in the respiratory tract</p>
</wx:argument><wx:argument name="rivista">
<p id="wx362">Curr Drug Targets</p>
</wx:argument><wx:argument name="volume">
<p id="wx363">7</p>
</wx:argument><wx:argument name="numero">
<p id="wx364">8</p>
</wx:argument><wx:argument name="pagine">
<p id="wx365">1005-10</p>
</wx:argument><wx:argument name="anno">
<p id="wx366">2006 Aug</p>
</wx:argument><wx:argument name="id">
<p id="wx367">PMID 16918328</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t9"><wx:argument name="autore">
<p id="wx368">Lecci A, Capriati A, Altamura M, Maggi CA</p>
</wx:argument><wx:argument name="titolo">
<p id="wx369">Tachykinins and tachykinin receptors in the gut, with special reference to NK2 receptors in human</p>
</wx:argument><wx:argument name="rivista">
<p id="wx370">Auton Neurosci</p>
</wx:argument><wx:argument name="volume">
<p id="wx371">126-127</p>
</wx:argument><wx:argument name="numero"/><wx:argument name="pagine">
<p id="wx372">232-49</p>
</wx:argument><wx:argument name="anno">
<p id="wx373">2006 Jun 30</p>
</wx:argument><wx:argument name="id">
<p id="wx374">PMID 16616700</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t10"><wx:argument name="autore">
<p id="wx375">Zhang Y, Berger A, Milne CD, Paige CJ</p>
</wx:argument><wx:argument name="titolo">
<p id="wx376">Tachykinins in the immune system</p>
</wx:argument><wx:argument name="rivista">
<p id="wx377">Curr Drug Targets</p>
</wx:argument><wx:argument name="volume">
<p id="wx378">7</p>
</wx:argument><wx:argument name="numero">
<p id="wx379">8</p>
</wx:argument><wx:argument name="pagine">
<p id="wx380">1011-20</p>
</wx:argument><wx:argument name="anno">
<p id="wx381">2006 Aug</p>
</wx:argument><wx:argument name="id">
<p id="wx382">PMID 16918329</p>
</wx:argument></wx:templatearguments>
<wx:templatearguments for="wx_t11"><wx:argument name="immagine1_nome">
<p id="wx383">Neurokinin A.png</p>
</wx:argument><wx:argument name="immagine1_dimensioni">
<p id="wx384">300px</p>
</wx:argument><wx:argument name="immagine1_descrizione">
<p id="wx385">Neurochinina A</p>
</wx:argument><wx:argument name="immagine2_nome"/><wx:argument name="immagine2_dimensioni"/><wx:argument name="immagine2_descrizione"/><wx:argument name="immagine3_nome"/><wx:argument name="immagine3_dimensioni"/><wx:argument name="immagine3_descrizione"/><wx:argument name="immagine4_nome"/><wx:argument name="immagine4_dimensioni"/><wx:argument name="immagine4_descrizione"/><wx:argument name="immagine5_nome"/><wx:argument name="immagine5_dimensioni"/><wx:argument name="immagine5_descrizione"/><wx:argument name="nome_IUPAC"/><wx:argument name="PubChem">
<p id="wx386">55582</p>
</wx:argument><wx:argument name="MeSHName">
<p id="wx387">Neurokinin+A</p>
</wx:argument><wx:argument name="abbreviazioni"/><wx:argument name="nomi_alternativi"/><wx:argument name="titolo_caratteristiche_generali"/><wx:argument name="formula">
<p id="wx388">C<sub id="wx389">50</sub>H<sub id="wx390">80</sub>N<sub id="wx391">14</sub>O<sub id="wx392">14</sub>S</p>
</wx:argument><wx:argument name="massa_molecolare">
<p id="wx393">1133,32</p>
</wx:argument><wx:argument name="peso_formula"/><wx:argument name="aspetto"/><wx:argument name="numero_CAS">
<p id="wx394">86933-74-6</p>
</wx:argument><wx:argument name="numero_EINECS"/><wx:argument name="titolo_proprietà_chimico_fisiche"/><wx:argument name="densità_condensato"/><wx:argument name="densità_g_l"/><wx:argument name="densità_gas"/><wx:argument name="prodotto_ionico"/><wx:argument name="indice_di_rifrazione"/><wx:argument name="Ka"/><wx:argument name="Ka_temperatura"/><wx:argument name="Kb"/><wx:argument name="Kb_temperatura"/><wx:argument name="punto_isoelettrico"/><wx:argument name="solubilità_acqua"/><wx:argument name="Ks"/><wx:argument name="Ks_temperatura"/><wx:argument name="temperatura_di_fusione"/><wx:argument name="entalpia_di_fusione"/><wx:argument name="entropia_di_fusione"/><wx:argument name="temperatura_di_ebollizione"/><wx:argument name="entalpia_di_ebollizione"/><wx:argument name="entropia_di_ebollizione"/><wx:argument name="punto_triplo"/><wx:argument name="punto_critico"/><wx:argument name="tensione_di_vapore"/><wx:argument name="tensione_di_vapore_temperatura"/><wx:argument name="sistema_cristallino"/><wx:argument name="viscosità_cinematica"/><wx:argument name="viscosità_cinematica_temperatura"/><wx:argument name="viscosità_dinamica"/><wx:argument name="viscosità_dinamica_temperatura"/><wx:argument name="titolo_proprietà_termochimiche"/><wx:argument name="entalpia_standard_di_formazione"/><wx:argument name="energia_libera_standard_di_formazione"/><wx:argument name="entropia_standard_di_formazione"/><wx:argument name="capacità_termica"/><wx:argument name="entalpia_standard_di_combustione"/><wx:argument name="titolo_proprietà_tossicologiche"/><wx:argument name="LD50"/><wx:argument name="flash_point"/><wx:argument name="limiti_di_esplosione"/><wx:argument name="temperatura_di_autoignizione"/><wx:argument name="TLV"/><wx:argument name="simbolo1"/><wx:argument name="simbolo2"/><wx:argument name="simbolo3"/><wx:argument name="simbolo4"/><wx:argument name="simbolo5"/><wx:argument name="frasiR"/><wx:argument name="frasiS"/></wx:templatearguments>
<wx:templatearguments for="wx_t12"><wx:argument name="Name">
<p id="wx395">Precursore 1 della tachichinina</p>
</wx:argument><wx:argument name="caption">
<p id="wx396">Precursore della Tachichinina A</p>
</wx:argument><wx:argument name="image">
<p id="wx397">Substance_P.png</p>
</wx:argument><wx:argument name="width">
<p id="wx398">280</p>
</wx:argument><wx:argument name="HGNCid">
<p id="wx399">11517</p>
</wx:argument><wx:argument name="Symbol">
<p id="wx400">TAC1</p>
</wx:argument><wx:argument name="AltSymbols">
<p id="wx401">TAC2, NKNA</p>
</wx:argument><wx:argument name="EntrezGene">
<p id="wx402">6863</p>
</wx:argument><wx:argument name="OMIM">
<p id="wx403">162320</p>
</wx:argument><wx:argument name="RefSeq">
<p id="wx404">NM_013998</p>
</wx:argument><wx:argument name="UniProt">
<p id="wx405">P20366</p>
</wx:argument><wx:argument name="PDB"/><wx:argument name="ECnumber"/><wx:argument name="Chromosome">
<p id="wx406">7</p>
</wx:argument><wx:argument name="Arm">
<p id="wx407">q</p>
</wx:argument><wx:argument name="Band">
<p id="wx408">21</p>
</wx:argument><wx:argument name="LocusSupplementaryData">
<p id="wx409">-q22</p>
</wx:argument></wx:templatearguments>
</html>
